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• Rhodiola

  27Mar
  Categories: FocusUp, The Edge Comments: 0

  Rhodiola:

  Rhodiola is a plant that has been used medicinally for centuries. Since 1960, more than 180 modern pharmacological, phytochemical and clinical studies have been published.⁴ “Rhodiola has demonstrated a remarkable ability to enhance cellular energy metabolism. The studies published thus far show the herb to be highly beneficial for both physical and mental performance under stress. It provides significant enhancement of mental energy and eliminates fatigue. It stimulates norepinephrine, dopamine and serotonin and has cholinergic effects in the central nervous system. Rhodiola also supports and enhances the effects of these neurotransmitters by increasing the delivery of precursors (building blocks) that can be utilized to produce dopamine and serotonin.” ⁵

  A randomized, double-blind and placebo-controlled trial studied the effect of Rhodiola on young, healthy physicians on night duty. The researchers measured rhodiola’s effect on five different meatures of mental acuity: associative thinking, short-term memory, calculation, concentration and speed of audiovisual perception. It was concluded that statistically significant improvements in all five of those mental performance parameters in the physicians who took Rhodiola rosea for two weeks. ⁶

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  4: Brown R, Gerbarg P, Ramazanov Z. Rhodiola rosea: A Phytomedicinal Overview View HerbalGram. 2002;56:40-52. American Botanical Council.

  5: Smith K, Brighter Minds, pp320. Brighter Mind Media Group, Ltd., Corinth TX. 2007

  6: Darbinyan V, Kteyan A, Panossian A, et al. Rhodiola rosea in stress induced fatigue-a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine. 2000 Oct;7(5):365-71.

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• Acetyl L Carnitine

  25Mar
  Categories: FocusUp, The Edge Comments: 0

  Acetyl L Carnitine:

  Acetyl-L-carnitine (ALCAR) is a form of L-carnitine, an amino acid that is found in nearly all cells of the body. ALCAR protects, maintains and energizes the neurons that are so critical to your memories, learning, mental energy and overall health.

  Scientists have confirmed that this form of carnitine is the most bioavailable and energetically useful form for your brain. It supports your brain’s optimal synthesis of acetylcholine, the neurotransmitter that is critical for learning and memory and that tends to be depleted in people with Alzheimer’s disease. ²

  A meta-analysis (a group of studies on the same subject) was conducted to show the results of ALCAR as a treatment for mild Alzheimer’s disease and other mild forms of cognitive impairment. The study showed a significant advantage for ALCAR compared to the placebo. An analysis of the psychometric tests showed that ALCAR had the most dramatic effects on the memory and intellectual functions. ³

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  2: Smith K, Brighter Minds, pp 239. Brighter Mind Media Group, Ltd., Corinth TX. 2007

  3: Montgomery SA, Thal LJ Amrein R. Meta-analysis of double-blind randomized controlled clinical trials of acetyl L carnitine versus placebo in the treatment of mild cognitive impairment and mild alzheimer’s disease. Int Clin Psychopharmacol 2003;18:61-71.

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• DMAE

  23Mar
  Categories: FocusUp, The Edge Comments: 0

  DMAE:

  DMAE, also known as dimethylethanolamine is believed to work primarily by supporting optimal neurotransmitter function, particularly the production and action of acetylcholine, which a crucial neurotransmitter responsible for relaying messages between brain cells. DMAE is naturally found in fish like sardines and anchovies and boosts levels of choline, an amino acid in the brain, this in turn, increases the brain’s production of acetylcholine.

  “Since DMAE is normally found within the human brain and is a precursor of the neurotransmitter acetylcholine and the neuronal membrane component phosphatidylcholine, it seems only sensible that DMAE should have diverse and positive effects on brain function. DMAE has been observed to accelerate the synthesis of phosphatidylcholine, and its incorporation into neuronal cell membranes. Within the brain, DMAE has antioxidant activity: more specifically, it acts as a potent intra-membrane scavenger of hydroxyl free radicals while stimulating oxidative metabolism in the cerebral cortex.” ¹

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  1: Smith K, Brighter Minds, pp 250. Brighter Mind Media Group, Ltd., Corinth TX. 2007

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• Huperzine A

  21Mar
  Categories: FocusUp, The Edge, Xooma News Comments: 0

  Huperzine A:

  Huperzine A is an alkaloid derived from the Chinese club moss Huperzia serrata. It promotes memory and cognitive function by supporting healthy acetylcholine levels in the brain, vascular function and neuronal health.

  Several randomized, double-blind, placebo-controlled trials indicate that Huperzine A supports memory and cognitive function.

  Here are some of the conclusions to those studies:

  ” A placebo-controlled randomized clinical trial of 34 pairs of adolescents complaining of self-diagnosed “memory inadequacy,” four weeks of supplemental Huperzine A resulted in significantly improved performance on tests of memory and learning ability. ⁷

  ” Clinical trials in China have demonstrated that Huperzine A significantly relieves memory deficits in aged subjects, patients with benign senescent forgetfulness, Alzheimer’s disease (AD) and vascular dementia (VD), with minimal peripheral cholinergic side effects compared with other AChEIs in use. ⁸

  ” Huperzine A possesses the ability to protect cells against hydrogen peroxide, beta-amyloid protein (a toxic protein seen in Alzheimer’s disease), glutamate (a neurotoxin), and ischemia (state of reduced oxygen). ⁹

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  8: Sunn QQ, Xu SS, Pan JL, Guo HM, Cao WQ. Huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent student. Acta Pharmacol Sin. 1999;20(70):601-603.

  7: Wang R, Tang XC. Neuroprotective effects of Huperzine A. A natural cholinesterase inhibitor for the treatment of Alzheimer’s disease. Neurosignals. 2005;14(1-2):71-82.

  9: Wang R, Yan H, Tang XC. Progress in studies of Huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol Sin. 2006;27(1):1-26

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• Maximize your edge with Xooma’s Xtreme X2O

  19Mar
  Categories: FocusUp, The Edge Comments: 0

  When you drink EDGE you’re providing your body with premium quality natural ingredients scientifically proven togive you clean, abundant energy and a sharp mind. But, did you know Xooma is well-known for another exclusive product that transforms your water into a powerful health & fitness beverage?

  Discover Xtreme X2O

  Xtreme X2O is an all-natural, organic mineral complex which will hydrate, mineralize, and revitalize your body. No other “enhanced water” or sports beverage on the market today can compare to “X2O.”

  Find out more here >>>

• Green Tea

  17Mar
  Categories: FocusUp, The Edge Comments: 0

  

  Green tea has been used in traditional medicine for centuries. The bulk of the science shows the polyphenols known as catechins and further identified as epigallocatechin gattate (EGCG) give green tea its unique and special power. For years, scientists have recognized that the catechins in green tea, specifically EGCG exhibit a powerful ability to protect brain cells from free radical activity.

  EGCG is receiving significant attention as a therapeutic agent for the treatment of neurodegenerative diseases involving brain regression. Researchers at the National Parkinson Foundation Centers of Excellence for Neurodegenerative Diseases Research stated:

  “Green tea catechins polyphenols, formally thought to be a simple radical scavenger, are now considered to invoke a spectrum of cellular mechanisms of action related to their neuroprotective activity. These include pharmacological activities like iron chelation, scavenging of radicals, activation of survival genes and cell signaling pathways, and regulation of mitochondrial function and possibly of the ubiquitin-proteasome system. As a consequence these compounds are receiving significant attention as therapeutic cytoprotective agents for the treatment of neurodegenerative and other diseases.” ¹⁰

  Another recent study showed that green tea actually slowed the effects of normal aging and its associated regression in brain function. Using an animal model, the effect of long-term green tea catechin intake was shown to effectively suppress further atrophy and cognitive dysfunction. The results of this study strongly suggest that green tea can halt the negative functional alterations that occur naturally in aging brains. ¹¹

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  10: Mandel S, Youdim MB. Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases. Free Radic Biol Med. 2004 Aug 1;37 (3):304-17.

  11: Unno K, Takabayashi F, Kishido T, Oku N. Suppressive effect of green tea catechins on morphologic and functional regression of the brain in aged mice with accelerated senescence (SAMP 10). Exp Gerontol. 2004 Jul;39(7): 1027-34

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• Green tea catechins linked to weight loss: Study

  15Mar
  Categories: FocusUp, The Edge Comments: 0

  By Lorraine Heller, 26-Jan-2009

  Antioxidant compounds in green tea could help promote exercise-induced abdominal fat loss, according to a new study from the American Society of Nutrition.

  Cetechins are a sub-class of flavonoids, or antioxidant compounds. Green tea is a rich source of catechins, which are thought to play a beneficial role in reducing the risk of various diseases, including Alzheimer’s, certain cancers, cardiovascular and oral health.

  Precious studies have also suggested that tea catechins may help promote weight loss. The current study, published in The Journal of Nutrition, found that consuming a beverage containing green tea catechins (625mg/d) may enhance exercise-induced loss of abdominal fat and improve triglyceride levels.

  Double-blind

  Researchers recruited just over 100 adults between the ages of 21 and 65. The participants were all healthy and “normally sedentary”, with a mean BMI of 32kg/m². Most subjects were of non-Hispanic white ethnicity.

  Male participants, who made up about half of the total study group, had a waist circumference of over 90cm, while women had a waist circumference of over 87cm. Cholesterol levels were over 5.2mmol/L.

  The subjects were randomly assigned to receive either 500ml per day of a beverage providing 625mg catechins, or a control beverage containing added caffeine to match the caffeine content of the catechin beverage.

  Both the active and the control beverage contained water, sodium chloride, artificial citrus flavouring, glucose, erythritol, and sucralose. Each 500ml serving provided 63kj (15 Kcal) of energy. Participants agreed not to consume more than two caffeinated beverages per day, including the study product, during the 12-week study period.

  Participants consumed one serving of their assigned beverage per day, at any time of the day, and with or without food. They continued their usual energy intake, and three-day diet records were taken at baseline, six and 12 weeks.

  During the study period, the subjects committed to 180 minutes of “moderate-intensity” physical activity per week, and to attend at lease three supervised exercise sessions per week.

  Body weight loss

  At the end of the study period, people in the catechin group were found to have lost more body weight compared to the control group (P = 0.079).

  There were no significant differences between the two groups in changes in waist circumference or fat mass. However, both total abdominal fat area (P = 0.013) and abdominal subcutaneous fat area (P = 0.019) had decreased more in the catechin group.

  The researchers concluded: “The findings of this study suggest that consumption of a beverage containing green tea catechins (625mg/d) may enhance exercise-induced loss of abdominal fat and improve circulating FFA and TG levels. Additional research is warranted to further clarify the mechanisms responsible for these effects

  Source:
  Tea catechins and exercise-induced weight loss
  The Journal of Nutrition
  doi: 10.3945/jn. 108098293
  Authors: Kevin C. Maki, Matthew S. Reeves, Mildred Farmer, Koichi Yasunaga, Noboru Matsuo, Yoshihisa Katsuragi, Masanori Komikado, Ichiro Tokimitsu, Donna Wilder, Franz Jones, Jeffrey B. Blumberg and Yolanda Cartwright

  

• Ingredient Science – The EDGE

  13Mar
  Categories: FocusUp, The Edge Comments: 0

  Memory loss and lack of energy are two of the most common complaints of aging in the world today. These ingredients have been studied, documented and boast proven results. In addition, their incredible synergistic effects provide the targeted nourishment your mind and body need when combined together.

  Green Tea: Green tea has been used in traditional medicine for centuries.

  Huperzine A: Huperzine A is an alkaloid derived from the Chinese club moss Huperzia serrata. It promotes memory and cognitive function by supporting healthy acetylcholine levels in the brain, vascular function and neuronal health.

  DMAE: DMAE, also known as dimethylethanolamine is believed to work primarily by supporting optimal neurotransmitter function, particularly the production and action of acetylcholine, which a crucial neurotransmitter responsible for relaying messages between brain cells. DMAE is naturally found in fish like sardines and anchovies and boosts levels of choline, an amino acid in the brain, this in turn, increases the brain’s production of acetylcholine.

  Acetyl L Carnitine: Acetyl-L-carnitine (ALCAR) is a form of L-carnitine, an amino acid that is found in nearly all cells of the body. ALCAR protects, maintains and energizes the neurons that are so critical to your memories, learning, mental energy and overall health.

  Rhodiola: Rhodiola is a plant that has been used medicinally for centuries. Since 1960, more than 180 modern pharmacological, phytochemical and clinical studies have been published.⁴ “Rhodiola has demonstrated a remarkable ability to enhance cellular energy metabolism. The studies published thus far show the herb to be highly beneficial for both physical and mental performance under stress.

• Drink EDGE and lose weight?

  12Mar
  Categories: FocusUp, The Edge Comments: 0

  Obesity is a rapidly growing global problem that many face in today’s society.  People are looking to do all they can to fight the battle of the bulge.  According to a new study from the American Society of Nutrition, antioxidant compounds found in green tea catechins were linked to weight loss.  Green tea is a rich source of catechins, which are thought to play a beneficial role in reducing the risk of various diseases, including Alzheimer’s, certain cancers, cardiovascular and oral health.  Now studies show that this powerful compound could help promote weight loss.

  Did you know that Green Tea is one of the key ingredients found in Xooma EDGE?

  Green Tea is also found in one of Xooma’s most popular products, EDGE.  With only 10 calories per serving and zero sugar, it’s the perfect addition to any weight loss program. And beyond the potential weight loss benefits, EDGE is designed to increase your energy levels while dramatically improving your mental clarity and focus.

  Find out more here >>>

• Tired of hearing about doom and gloom in the global economy?

  11Mar
  Categories: Xooma Business Opportunity, Xooma News, Xooma Xcel Comments: 0

  Are you like us? Are you sick and tired of hearing about the doom and gloom in the global economy?

  Don’t get us wrong…we’re not saying it isn’t serious problem…but have you noticed that the numerous “bailout” programs government officials have created have done almost nothing to directly help you and your family? Worse yet, with billions of dollars already spent in an attempt to “fix” today’s economy, tens of thousands of people are still losing their jobs every day with no end in sight.

  Think about it. If you can’t rely on your job or the government to provide financial stability for you and your family…what do you do?

  You create your own “economic stimulus package” with Xooma Xcel!

  Pre-Launch Position – XCELerate with XOOMA

  What is Xooma Xcel?

  It’s your opportunity to break out of the daily “rat race,” stop living in fear and create the kind of financial abundance you and your family deserve – regardless of how bad the economy is.

  Want to Xcelerate your success with Xooma Worldwide? If so, click on the links below in the exact order they are listed to reveal Xooma’s exciting new “Prosperity Plan” – launching March 1st.

  This quote from a top industry analyst sums it up…

  “Never before in history have there been so many people actively looking to start a home-based business. And thanks to technology, it’s never been more realistic for the average person to succeed.”

  Ready to make history? We are.